George M Grunert MD, Reproductive Endocrinologist, HFS IVF Program Director


  • Infertility can weigh heavily on men, women

    Throughout history, infertility has mainly been seen as a female problem, but the reality is far from that. When it comes to couples trying to have a baby, infertility is evenly distributed between the sexes: 30 percent due to male problems, 30 percent female, 10 percent male and female combined and 20 percent unexplained. Age is a factor for both.

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  • Smoking Increases the Risk of Ectopic Pregnancy

    Cigarette smoke reduces the production of a Fallopian tube gene known as "BAD", which helps explain the link between smoking and ectopic pregnancy. The finding, from scientists led by Drs Andrew Horne and Colin Duncan at the Medical Research Council (MRC) Centre for Reproductive Health in Edinburgh, UK, was described at the annual meting of ESHRE (European Society of Human Reproduction and Embryology) in Istanbul.

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  • Unhealthy lifestyles have little impact on sperm quality

    Lifestyle advice given by doctors to men diagnosed with infertility should be radically overhauled according to research published June 13.

    This potentially overturns much of the current advice given to men about how they might improve their fertility and suggests that many common lifestyle risks may not be as important as we previously thought.

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  • 5 millionth IVF baby born this year

    Experts estimate that around now, approximately 5 million babies have been born as a result of assisted reproduction technologies - namely IVF and ICSF. The first test tube baby was born in July 1978, in England, her name was Louise Brown. These data were presented yesterday at the 28th Meeting of the European Society of Human Reproduction and Embryology (ESHRE), Istanbul, Turkey.

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  • Lower live birth rates in IVF likely when mother consumes high quantities of dietary fat

    Women with a higher intake of dietary saturated fats have fewer mature oocytes available for collection in IVF, according to results of a study from the Harvard School of Public Health funded by the US National Institutes of Health. The study investigated the effect of dietary fat (classified as total, saturated, monounsaturated, polyunsaturated, omega 6, omega 3 and trans) on a range of preclinical and clinical outcomes in women having IVF.

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  • The chance of IVF success reduced by around 50 percent by coffee consumption of 5 or more cups a day

    Women who drink five or more cups of coffee a day severely reduce their chance of success from IVF treatment. Indeed, Danish investigators who followed up almost 4000 IVF and ICSI patients described the adverse impact as "comparable to the detrimental effect of smoking".

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  • Vitamin D may increase IVF success – depending on race

    A woman's race may determine whether vitamin D helps them to conceive through IVF.

    The sunshine vitamin is famed for its benefit to bones and the immune system, but it also plays a role in conception. Now, evidence suggests that the vitamin's benefits may only apply to certain racial groups – while white women can boost their IVF success rates with vitamin D, the opposite appears to be true for Asian women.

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  • Should 3-parent IVF be allowed to avoid disease?

    Britain launched a public consultation today to ask whether controversial “three-parent” fertility treatments should be available to families hoping to avoid passing on incurable diseases.

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  • Link between sperm DNA quality in older men improved nutrition

    A new study led by scientists from the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) found that a healthy intake of micronutrients is strongly associated with improved sperm DNA quality in older men. In younger men, however, a higher intake of micronutrients didn't improve their sperm DNA.

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  • Study provides insight into why severely obese women have difficulty getting pregnant from IVF

    According to Dr. Racowsky, in order for an egg to have the best chance of fertilizing and supporting embryo development, it should be "mature" with one spindle (a critical egg structure) on which is attached one organized set of chromosomes. This study found severely obese women have a much greater chance of having eggs with multiple spindles and disorganized chromosomes.

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