George M Grunert MD, Reproductive Endocrinologist, HFS IVF Program Director

Traffic Cop for Meiosis - With Implications for Fertility, Birth Defects

Traffic Cop for Meiosis - With Implications for Fertility, Birth Defects
Researchers at New York University and the Whitehead Institute for Biomedical Research have identified the mechanism that plays "traffic cop" in meiosis - the process of cell division required in reproduction. Their findings, which appear in the journal eLife, shed new light on fertility and may lead to greater understanding of the factors that lead to birth defects.

Researchers at New York University and the Whitehead Institute for Biomedical Research have identified the mechanism that plays "traffic cop" in meiosis - the process of cell division required in reproduction. Their findings, which appear in the journal eLife, shed new light on fertility and may lead to greater understanding of the factors that lead to birth defects.

"We have isolated a checkpoint that is necessary for a genome's viability and for normal development," said Andreas Hochwagen, an assistant professor in NYU's Department of Biology, who co-authored the paper with Hannah Blitzblau, a researcher at the Whitehead Institute for Biomedical Research. "Without this restraining mechanism, chromosomes can end up irreversibly broken during meiosis."

Source: ScienceDaily

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