Aspire Fertility Medical Director

Pre-implantation Genetic Diagnosis for Genetic Diseases

Pre-implantation genetic diagnosis (PGD) is a test performed prior to in vitro fertilization (IVF) to detect genetic and chromosomal abnormalities or defects in the embryo prior to its implantation into the mother’s womb. PGD is indicated for the following:

  • Your child has a risk of being born with an inherited genetic condition
  • You or your partner has a family history of chromosomal abnormalities
  • Previous pregnancy with genetic abnormality
  • Recurrent miscarriage
  • Advanced maternal age

PGD testing is performed on a 3-day old embryo. A few cells are extracted from the embryo and tested for different conditions. Embryos which clear the test and are unaffected by any kind of genetic conditions or abnormalities are used for implantation. Some of the conditions that can be diagnosed using PGD are cystic fibrosis, Down’s syndrome, thalassemia, and hereditary breast and ovarian cancer.


Aspire Fertility Institute Houston Southwest Women’s Health Alliance